Concept information
Preferred term
Motor Neuron Disease
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Motor System Disease
- Motor System Diseases
Note
- general or unspecified; prefer specifics
Scope note
- Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
History note
- 92
In other languages
-
Finnish
-
ALS
-
amyotrofinen lateraaliskleroosi
-
atrophia musculorum spinalis progressiva
-
etenevä bulbaaripareesi
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etenevä spinaalinen lihasatrofia
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etenevä ydinjatkehalvaus
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familjär motorneuronsjukdom
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lateralskleros amyotrofisk
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lateralskleros primär
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morbus motoneuronalis
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morbus motoneuronalis familialis
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motoneuronisairaudet
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motoneuronitaudit
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motoneuronitauti
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motorneuronsjukdom
-
paresis bulbaris progressiva
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primaarinen lateraaliskleroosi
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progressiv bulbärpares
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progressiv spinal muskelatrofi
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sclerosis lateralis amyotrophica
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sclerosis lateralis primaria
-
suvuittainen motoneuronisairaus
-
Swedish
URI
http://www.yso.fi/onto/mesh/D016472
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