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... > Heterocyclic Compounds > Heterocyclic Compounds, Fused-Ring > Heterocyclic Compounds, 2-Ring > Benzopyrans > Aflatoxins > Aflatoxin B1
... > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyrans > Benzopyrans > Aflatoxins > Aflatoxin B1
Biological Factors > Toxins, Biological > Mycotoxins > Aflatoxins > Aflatoxin B1

Preferred term

Aflatoxin B1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Aflatoxin B(1)

Note

  • /antag permitted but consider also ANTITOXINS

Scope note

  • A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and causes immunosuppression in animals. It is found as a contaminant in peanuts, cottonseed meal, corn, and other grains. The mycotoxin requires epoxidation to aflatoxin B1 2,3-oxide for activation. Microsomal monooxygenases biotransform the toxin to the less toxic metabolites aflatoxin M1 and Q1.

History note

  • 92; was AFLATOXIN B1 (NM) 1980-91

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URI

http://www.yso.fi/onto/mesh/D016604

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