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Concept information

... > Biological Factors > Inflammation Mediators > Autacoids > Eicosanoids > Prostaglandins > Prostaglandins, Synthetic > Prostaglandins E, Synthetic > Rioprostil
... > Lipids > Fatty Acids > Fatty Acids, Unsaturated > Eicosanoids > Prostaglandins > Prostaglandins, Synthetic > Prostaglandins E, Synthetic > Rioprostil

Preferred term

Rioprostil  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • ORF 15927
  • ORF-15927
  • ORF15927
  • RWJ 15927
  • RWJ-15927
  • RWJ15927
  • TR 4698
  • TR-4698
  • TR4698

Scope note

  • A synthetic methylprostaglandin E1 analog that reduces gastric acid secretion and enhances the gastric mucus-bicarbonate barrier. It is effective in the therapy of gastric ulcers and gives significant protection against NSAID-induced gastric mucosal damage. The drug also prevents cyclosporin A-induced damage to endocrine and exocrine pancreatic secretions. It shows a low order of acute toxicity and there is no evidence of embryotoxicity, fetotoxicity, teratogenicity, or mutagenicity in animal studies.

History note

  • 92; was RIOPROSTIL (NM) 1985-91

In other languages

URI

http://www.yso.fi/onto/mesh/D016630

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