Concept information
Preferred term
Primary Ovarian Insufficiency
Type
-
Topical Descriptor
Broader concept
Entry terms
- Ovarian Failure, Premature
- Premature Ovarian Failure
Scope note
- Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections. The most commonly known genetic cause is the expansion of a CGG repeat to 55 to 199 copies in the 5' untranslated region in the X-linked FMR1 gene.
History note
- 2011(1992)
In other languages
-
Finnish
-
ennenaikainen menopaussi
-
ennenaikainen munasarjojen vajaatoiminta
-
för tidig menopaus UNS
-
hyposecretio oestrogenorum
-
insufficientia ovariorum primaria
-
menopausis praecox NAS
-
minskad mängd estrogener
-
naishormonien vajaus
-
primär ovarial svikt
-
resistent ovarium
-
resistentin munasarjan oireyhtymä
-
resistentin munasarjan syndrooma
-
syndroma ovarii resistantis
-
tarkemmin määrittämätön ennenaikainen menopaussi
-
Swedish
-
Primär ovarialsvikt
-
Resistent ovariesyndrom
URI
http://www.yso.fi/onto/mesh/D016649
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