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Biological Factors > Blood Coagulation Factor Inhibitors > Lupus Coagulation Inhibitor
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Antibodies > Autoantibodies > Antibodies, Antiphospholipid > Lupus Coagulation Inhibitor
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Antibodies > Autoantibodies > Antibodies, Antiphospholipid > Lupus Coagulation Inhibitor
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Antibodies > Autoantibodies > Antibodies, Antiphospholipid > Lupus Coagulation Inhibitor

Preferred term

Lupus Coagulation Inhibitor  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Anticoagulant Autoantibody, Lupus
  • Anticoagulant, Lupus
  • Autoantibody, Lupus Anticoagulant
  • Coagulation Inhibitor, Lupus
  • Inhibitor, Lupus Coagulation
  • Lupus Anticoagulant
  • Lupus Anticoagulant Autoantibodies
  • Lupus Anticoagulant Autoantibody

Scope note

  • An antiphospholipid antibody found in association with a variety of diseases (e.g., SYSTEMIC LUPUS ERYTHEMATOSUS and ANTIPHOSPHOLIPID SYNDROME) as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.

History note

  • 92; was LUPUS COAGULATION INHIBITOR (NM) 1978-91

In other languages

URI

http://www.yso.fi/onto/mesh/D016682

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