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Concept information

Preferred term

Monocrotaline  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Monocrotaline, (all-xi)-Isomer
  • Monocrotaline Hydrochloride (13alpha,14alpha)-Isomer

Scope note

  • A pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes are noted after oral magnesium treatment.

History note

  • 92; was MONOCROTALINE (NM) 1973-91

In other languages

URI

http://www.yso.fi/onto/mesh/D016686

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