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Amino Acids, Peptides, and Proteins > Proteins > Nerve Tissue Proteins > Synapsins
Amino Acids, Peptides, and Proteins > Proteins > Phosphoproteins > Synapsins

Preferred term

Synapsins  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Synapsin

Scope note

  • A family of synaptic vesicle-associated proteins involved in the short-term regulation of NEUROTRANSMITTER release. Synapsin I, the predominant member of this family, links SYNAPTIC VESICLES to ACTIN FILAMENTS in the presynaptic nerve terminal. These interactions are modulated by the reversible PHOSPHORYLATION of synapsin I through various signal transduction pathways. The protein is also a substrate for cAMP- and CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES. It is believed that these functional properties are also shared by synapsin II.

History note

  • 1992; use SYNAPSINS (NM) 1981-1991

In other languages

URI

http://www.yso.fi/onto/mesh/D016704

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