Concept information
Preferred term
Genes, fos
Type
-
Topical Descriptor
Broader concept
Entry terms
- fos Gene
- fos Genes
Note
- fos stands for "Finkel" & "Osteogenic Sarcoma"
Scope note
- Retrovirus-associated DNA sequences (fos) originally isolated from the Finkel-Biskis-Jinkins (FBJ-MSV) and Finkel-Biskis-Reilly (FBR-MSV) murine sarcoma viruses. The proto-oncogene protein c-fos codes for a nuclear protein which is involved in growth-related transcriptional control. The insertion of c-fos into FBJ-MSV or FBR-MSV induces osteogenic sarcomas in mice. The human c-fos gene is located at 14q21-31 on the long arm of chromosome 14.
History note
- 92
In other languages
-
Finnish
-
fos-geeni
-
Swedish
-
c-fos gener
-
c-fos proto-onkogener
-
v-fos gener
-
v-fos onkogener
URI
http://www.yso.fi/onto/mesh/D016762
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