Concept information
Preferred term
CD4 Immunoadhesins
Type
-
Topical Descriptor
Entry terms
- Immunoadhesins, CD4
Scope note
- Chimeric molecules resulting from the fusion of recombinant soluble CD4 to the Fc portion of immunoglobulins. These have potential use in the therapy of AIDS since they possess both the gp120-binding and HIV-blocking properties of rCD4 as well as the long plasma half-life and Fc receptor-binding functions of immunoglobulin.
History note
- 92; was CD4 IMMUNOADHESIN (NM) 1989-91
In other languages
-
Finnish
-
CD4-immunoadhesiini
-
Swedish
URI
http://www.yso.fi/onto/mesh/D016860
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