Concept information
Preferred term
Polyendocrinopathies, Autoimmune
Type
-
Topical Descriptor
Broader concept
Entry terms
- Polyglandular Type I Autoimmune Syndrome
- Polyglandular Type II Autoimmune Syndrome
- Polyglandular Type III Autoimmune Syndrome
Note
- do not coordinate with specific endocrine disease term or CANDIDIASIS unless particularly discussed
Scope note
- Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
History note
- 1992
In other languages
-
Finnish
-
Swedish
-
Autoimmun polyendokrinopati-candidiasis-ektodermal dystrofi
-
Autoimmunt polyglandulärt syndrom typ I
-
Autoimmunt polyglandulärt syndrom typ II
-
Autoimmunt polyglandulärt syndrom typ III
-
Schmidts syndrom
URI
http://www.yso.fi/onto/mesh/D016884
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