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... > Biological Factors > Intercellular Signaling Peptides and Proteins > Cytokines > Interferons > Interferon Type I > Interferon-alpha
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Cytokines > Interferons > Interferon Type I > Interferon-alpha
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Cytokines > Interferons > Interferon Type I > Interferon-alpha

Preferred term

Interferon-alpha  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • alpha Interferon
  • alpha-Interferon
  • Interferon Alfa
  • Interferon, alpha
  • Interferon, Leukocyte
  • Interferon, Lymphoblast
  • Interferon, Lymphoblastoid
  • Leukocyte Interferon
  • Lymphoblast Interferon
  • Lymphoblastoid Interferon

Scope note

  • One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.

History note

  • 1992; for INTERFERON, LYMPHOBLAST and INTERFERON, LEUKOCYTE use INTERFERON TYPE I 1989-1991

In other languages

URI

http://www.yso.fi/onto/mesh/D016898

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