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... > Biological Factors > Antigens > Antigens, Surface > Antigens, Differentiation > Antigens, Differentiation, T-Lymphocyte > CD3 Complex
Biological Factors > Biomarkers > Antigens, Differentiation > Antigens, Differentiation, T-Lymphocyte > CD3 Complex

Preferred term

CD3 Complex  

Type

  • Topical Descriptor

Broader concept

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Related concepts

Entry terms

  • Antigen, CD3
  • Antigens, CD3
  • Antigens, T3
  • Antigen, T3
  • CD3 Antigen
  • CD3 Antigens
  • T3 Antigen
  • T3 Antigens
  • T3 Complex

Scope note

  • Complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA).

History note

  • 2018 (1993); use T3 ANTIGEN COMPLEX 1983-92; use ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988-92

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URI

http://www.yso.fi/onto/mesh/D017252

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