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Concept information

... > Organic Chemicals > Lactones > Polyketides > Macrolides > Erythromycin > Clarithromycin
... > Polycyclic Compounds > Macrocyclic Compounds > Polyketides > Macrolides > Erythromycin > Clarithromycin

Preferred term

Clarithromycin  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 6-O-Methylerythromycin

Scope note

  • A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.

History note

  • 93; was CLARITHROMYCIN (NM) 1987-92

In other languages

URI

http://www.yso.fi/onto/mesh/D017291

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