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... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > RNA-Binding Proteins > RNA Splicing Factors > Ribonucleoprotein, U1 Small Nuclear
... > Amino Acids, Peptides, and Proteins > Proteins > Nucleoproteins > RNA-Binding Proteins > RNA Splicing Factors > Ribonucleoprotein, U1 Small Nuclear
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > RNA-Binding Proteins > Ribonucleoproteins > Ribonucleoproteins, Small Nuclear > Ribonucleoprotein, U1 Small Nuclear
... > Amino Acids, Peptides, and Proteins > Proteins > Nucleoproteins > RNA-Binding Proteins > Ribonucleoproteins > Ribonucleoproteins, Small Nuclear > Ribonucleoprotein, U1 Small Nuclear

Preferred term

Ribonucleoprotein, U1 Small Nuclear  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Ribonucleoproteins, Small, U1
  • Small Nuclear Ribonucleoproteins, U1
  • U1 Small Nuclear Ribonucleoproteins
  • U1 snRNP

Scope note

  • A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction.

History note

  • 2000; U1 SNRNP was U1-RNP (SY) to SMALL RIBONUCLEOPROTEINS (NM) 1982-92

In other languages

URI

http://www.yso.fi/onto/mesh/D017412

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RDF/XML TURTLE JSON-LD Created 5/22/92, last modified 7/5/16