Concept information
Preferred term
Ribonucleoprotein, U2 Small Nuclear
Type
-
Topical Descriptor
Broader concept
Entry terms
- Ribonucleoproteins, Small, U2
- Small Nuclear Ribonucleoproteins, U2
- U2 Small Nuclear Ribonucleoproteins
- U2 snRNP
Scope note
- A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U2 snRNP along with other small nuclear ribonucleoproteins (U1, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U2 snRNA forms base pairs with conserved sequence motifs at the branch point, which associates with a heat- and RNAase-sensitive factor in an early step of splicing.
History note
- 2000; U2 SNRNP was SNRNP-U2 (SY) to SMALL RIBONUCLEOPROTEINS (NM) 1982-92
In other languages
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Finnish
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Swedish
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U2 snRNP
URI
http://www.yso.fi/onto/mesh/D017413
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