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Concept information

Preferred term

Ribonucleoprotein, U2 Small Nuclear  

Type

  • Topical Descriptor

Entry terms

  • Ribonucleoproteins, Small, U2
  • Small Nuclear Ribonucleoproteins, U2
  • U2 Small Nuclear Ribonucleoproteins
  • U2 snRNP

Scope note

  • A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U2 snRNP along with other small nuclear ribonucleoproteins (U1, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U2 snRNA forms base pairs with conserved sequence motifs at the branch point, which associates with a heat- and RNAase-sensitive factor in an early step of splicing.

History note

  • 2000; U2 SNRNP was SNRNP-U2 (SY) to SMALL RIBONUCLEOPROTEINS (NM) 1982-92

URI

http://www.yso.fi/onto/mesh/D017413

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RDF/XML TURTLE JSON-LD Created 5/22/92, last modified 7/5/16