Concept information
Preferred term
Receptors, Somatomedin
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Insulin Like Growth Factor Receptor
- Insulin-Like Growth Factor Receptor
- Insulin Like Growth Factor Receptors
- Insulin-Like Growth Factor Receptors
- Receptors, Insulin Like Growth Factors
- Receptors, Insulin-Like Growth Factors
- Receptor, Somatomedin
- Somatomedin Receptor
- Somatomedin Receptors
Note
- specifics are also available
Scope note
- Cell surface receptors that bind somatomedins and trigger intracellular changes which influence the behavior of cells. Studies have disclosed two types of receptors for this family of peptide hormones. The type I receptor is homologous to the insulin receptor and has tyrosine kinase activity. The type II receptor is identical to the mannose-6-phosphate receptor which is important in trafficking of lysosomal enzymes.
History note
- 93; was INSULIN-LIKE GROWTH FACTOR RECEPTOR (NM) 1980-92; INSULIN-LIKE GROWTH FACTORS RECEPTORS was see RECEPTORS, SOMATOMEDIN 1993
In other languages
-
Finnish
-
IGF-reseptori
-
IGF-reseptorit
-
insuliininkaltaisen kasvutekijän reseptori
-
insuliininkaltaisen kasvutekijän reseptorit
-
somatomediinireseptori
-
Swedish
-
Receptorer, somatomedin
URI
http://www.yso.fi/onto/mesh/D017451
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