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Concept information

Preferred term

Leukocyte Common Antigens  

Type

  • Topical Descriptor

Entry terms

  • Antigen, CD45
  • Antigen, Leukocyte Common
  • Antigens, CD45
  • Antigens, L-CA
  • Antigens, T200
  • CD45 Antigen
  • CD45 Antigens
  • L CA Antigens
  • L-CA Antigens
  • Leukocyte Common Antigen
  • Protein Tyrosine Phosphatase, Receptor Type, C
  • T200 Antigens

Scope note

  • High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN TYPE III DOMAINS and possess cytoplasmic protein tyrosine phosphatase activity, which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. Leukocyte common antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons.

History note

  • 2018 (1993); for RT7 use HISTOCOMPATIBILITY ANTIGENS RT 1983-92; for B220 ANTIGEN use ANTIGENS, CD45 1990-95

In other languages

  • Finnish

  • leukosyyteille yhteinen antigeeni
  • leukosyyteille yhteiset antigeenit
  • leukosyyttien yhteinen antigeeni
  • leukosyyttien yhteiset antigeenit
  • valkosoluille yhteinen antigeeni
  • valkosoluille yhteiset antigeenit
  • valkosolujen yhteinen antigeeni
  • Swedish

  • CD45R0 antigener
  • CD45RA antigener
  • CD45RB antigener
  • L-CA antigener

URI

http://www.yso.fi/onto/mesh/D017493

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