Concept information
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Proteins
Membrane Proteins
Receptor-Like Protein Tyrosine Phosphatases
Receptor-Like Protein Tyrosine Phosphatases, Class 1
...
Intracellular Signaling Peptides and Proteins
Protein Tyrosine Phosphatases
Receptor-Like Protein Tyrosine Phosphatases
Receptor-Like Protein Tyrosine Phosphatases, Class 1
Preferred term
Leukocyte Common Antigens
Type
-
Topical Descriptor
Broader concept
Entry terms
- Antigen, CD45
- Antigen, Leukocyte Common
- Antigens, CD45
- Antigens, L-CA
- Antigens, T200
- CD45 Antigen
- CD45 Antigens
- L CA Antigens
- L-CA Antigens
- Leukocyte Common Antigen
- Protein Tyrosine Phosphatase, Receptor Type, C
- T200 Antigens
Scope note
- High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN TYPE III DOMAINS and possess cytoplasmic protein tyrosine phosphatase activity, which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. Leukocyte common antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons.
History note
- 2018 (1993); for RT7 use HISTOCOMPATIBILITY ANTIGENS RT 1983-92; for B220 ANTIGEN use ANTIGENS, CD45 1990-95
In other languages
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Finnish
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leukosyyteille yhteinen antigeeni
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leukosyyteille yhteiset antigeenit
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leukosyyttien yhteinen antigeeni
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leukosyyttien yhteiset antigeenit
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valkosoluille yhteinen antigeeni
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valkosoluille yhteiset antigeenit
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valkosolujen yhteinen antigeeni
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Swedish
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CD45R0 antigener
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CD45RA antigener
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CD45RB antigener
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L-CA antigener
URI
http://www.yso.fi/onto/mesh/D017493
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