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Concept information

Preferred term

Receptor, IGF Type 1  

Type

  • Topical Descriptor

Entry terms

  • IGF 1 Receptor
  • IGF-1 Receptor
  • IGF-1 Receptors
  • IGF I Receptor
  • IGF-I Receptor
  • IGF Type 1 Receptor
  • Insulin Like Growth Factor I Receptor
  • Insulin-Like-Growth Factor I Receptor
  • Receptor, IGF-1
  • Receptor, IGF I
  • Receptor, IGF-I
  • Receptor, Insulin-Like Growth Factor I
  • Receptor, Insulin-Like Growth Factor Type 1
  • Receptors, IGF 1
  • Receptors, IGF-1
  • Receptors, Insulin-Like-Growth Factor I

Scope note

  • A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The beta subunit contains an intrinsic tyrosine kinase domain.

History note

  • 2000(1993);

In other languages

URI

http://www.yso.fi/onto/mesh/D017526

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