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Concept information

Preferred term

Myelinolysis, Central Pontine  

Type

  • Topical Descriptor

Entry terms

  • Central Pontine Myelinoclasis
  • Central Pontine Myelinolysis
  • Myelinoclasis, Central Pontine
  • Pontine Myelinolysis, Central

Scope note

  • A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness. Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons. This condition is usually associated with systemic disorders such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1125-6)

History note

  • 1994

In other languages

  • Finnish

  • aivosillan keskiosien myelinolyysi
  • central pontin myelinolys
  • myelinolysis centralis pontis
  • myelinolysis pontis centralis
  • ponsin myelinolyysi
  • ponsin sentraalinen myelinolyysi
  • sentraalinen myelinolyysi
  • sentraalinen pontinen myelinolyysi
  • Swedish

  • Extrapontin myelinolys

URI

http://www.yso.fi/onto/mesh/D017590

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