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Concept information

Preferred term

Receptors, Glycine  

Type

  • Topical Descriptor

Entry terms

  • Glycine Receptor
  • Glycine Receptors
  • Receptor, Glycine

Scope note

  • Cell surface receptors that bind GLYCINE with high affinity and trigger intracellular changes which influence the behavior of cells. Glycine receptors in the CENTRAL NERVOUS SYSTEM have an intrinsic chloride channel. GlyA receptor is sensitive to STRYCHNINE and localized in the post-synaptic membrane of inhibitory glycinergic neurons. GlyB receptor is insensitive to strychnine and associated with the excitatory NMDA receptor.

History note

  • 1994; was GLYCINE RECEPTOR (NM) 1981-1993; for GLYCINE RECEPTOR ALPHA1 was under RECEPTORS, GLYCINE 1995-2020; for GLYCINE RECEPTOR ALPHA1 was under RECEPTORS, GLYCINE 1997-2020

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URI

http://www.yso.fi/onto/mesh/D018009

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