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... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Antibodies > Antibodies, Bispecific
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Antibodies > Antibodies, Bispecific
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Antibodies > Antibodies, Bispecific

Preferred term

Antibodies, Bispecific  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Antibodies, Bifunctional
  • Bifunctional Antibodies
  • Bispecific Antibodies

Note

  • do not coordinate with ANTIBODY FORMATION for /biosynthesis

Scope note

  • Antibodies, often monoclonal, in which the two antigen-binding sites are specific for separate ANTIGENIC DETERMINANTS. They are artificial antibodies produced by chemical crosslinking, fusion of HYBRIDOMA cells, or by molecular genetic techniques. They function as the main mediators of targeted cellular cytotoxicity and have been shown to be efficient in the targeting of drugs, toxins, radiolabeled haptens, and effector cells to diseased tissue, primarily tumors.

History note

  • 94

In other languages

URI

http://www.yso.fi/onto/mesh/D018033

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