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Concept information

Preferred term

Receptors, GABA  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • GABA Receptor
  • GABA Receptors
  • gamma Aminobutyric Acid Receptor
  • gamma-Aminobutyric Acid Receptor
  • gamma Aminobutyric Acid Receptors
  • gamma-Aminobutyric Acid Receptors
  • Receptor, GABA
  • Receptor, gamma-Aminobutyric Acid
  • Receptors, gamma Aminobutyric Acid
  • Receptors, gamma-Aminobutyric Acid

Scope note

  • Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.

History note

  • 94; GABA RECEPTORS & RECEPTORS, GAMMA-AMINOBUTYRIC ACID were see RECEPTORS, GABA-BENZODIAZEPINE 1985-93

In other languages

URI

http://www.yso.fi/onto/mesh/D018079

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