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Concept information

Preferred term

Mice, Inbred mdx  

Type

  • Topical Descriptor

Entry terms

  • Inbred mdx Mouse
  • mdx Mice
  • mdx Mouse
  • Mice, mdx
  • Mouse, Inbred mdx
  • Mouse, mdx

Note

  • NIM with no qualifiers when experimental animal

Scope note

  • A strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous animals that lack the muscle protein DYSTROPHIN, have high serum levels of muscle ENZYMES, and possess histological lesions similar to human MUSCULAR DYSTROPHY. The histological features, linkage, and map position of mdx make these mice a worthy animal model of DUCHENNE MUSCULAR DYSTROPHY.

History note

  • 94

In other languages

URI

http://www.yso.fi/onto/mesh/D018101

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