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Biological Factors > Antigens > Antigens, Surface > B7 Antigens > B7-1 Antigen
Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > B7 Antigens > B7-1 Antigen
Biological Factors > Intercellular Signaling Peptides and Proteins > B7 Antigens > B7-1 Antigen
Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > B7 Antigens > B7-1 Antigen
Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > B7 Antigens > B7-1 Antigen

Preferred term

B7-1 Antigen  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Antigen, B7 1
  • Antigen, B7-1
  • Antigens, CD80
  • B7 1 Costimulatory Molecule
  • B7-1 Costimulatory Molecule
  • B7 1 Ligand
  • B7-1 Ligand
  • B Cell Activation Antigen
  • B-Cell Activation Antigen
  • CD80 Antigen
  • CD80 Antigens
  • Costimulatory Molecule, B7-1
  • Ligand, B7-1

Scope note

  • A costimulatory ligand membrane glycoprotein that contains a V2 type and C2 IMMUNOGLOBULIN DOMAIN and is expressed by ANTIGEN-PRESENTING CELLS. It binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.

History note

  • 2018 (1991)

In other languages

URI

http://www.yso.fi/onto/mesh/D018122

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