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Concept information

Neoplasms > Neoplasms by Histologic Type > Neoplasms, Germ Cell and Embryonal > Mesonephroma > Endodermal Sinus Tumor

Preferred term

Endodermal Sinus Tumor  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Tumors, Yolk Sac
  • Tumor, Yolk Sac
  • Yolk Sac Tumor
  • Yolk Sac Tumors

Note

  • coordinate with precoordinated organ/neoplasm term

Scope note

  • An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumor found in children. It is characterized by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (Schiller-Duval body). The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1189)

History note

  • 94; was see MESONEPHROMA 1979-93; YOLK SAC TUMOR was see MESONEPHROMA 1979-93

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URI

http://www.yso.fi/onto/mesh/D018240

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RDF/XML TURTLE JSON-LD Created 6/25/93, last modified 7/6/09