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Amino Acids, Peptides, and Proteins > Proteins > Receptors, Cytoplasmic and Nuclear > Orphan Nuclear Receptors > Receptors, Aryl Hydrocarbon
Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Orphan Nuclear Receptors > Receptors, Aryl Hydrocarbon
Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Orphan Nuclear Receptors > Receptors, Aryl Hydrocarbon

Preferred term

Receptors, Aryl Hydrocarbon  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • AH Receptor
  • AH Receptors
  • Aryl Hydrocarbon Receptor
  • Aryl Hydrocarbon Receptors
  • Dioxin Receptor
  • Dioxin Receptors
  • Polyaromatic Hydrocarbon Receptor
  • Polyaromatic Hydrocarbon Receptors
  • Receptor, AH
  • Receptor, Aryl Hydrocarbon
  • Receptor, Dioxin
  • Receptor, Polyaromatic Hydrocarbon
  • Receptors, 2,3,7,8-Tetrachlorodibenzo-p-dioxin
  • Receptors, AH
  • Receptors, Dioxin
  • Receptors, Polyaromatic Hydrocarbon
  • Receptors, TCDD
  • Receptor, TCDD
  • TCDD Receptor
  • TCDD Receptors

Scope note

  • Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.

History note

  • 94; was ARYL HYDROCARBON RECEPTOR (NM) 1981-93; 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN RECEPTOR was (NM) 1979-93

In other languages

URI

http://www.yso.fi/onto/mesh/D018336

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RDF/XML TURTLE JSON-LD Created 7/9/93, last modified 6/23/15