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Investigative Techniques > Clinical Laboratory Techniques > Cytological Techniques > Patch-Clamp Techniques
Diagnosis > Diagnostic Techniques and Procedures > Clinical Laboratory Techniques > Cytological Techniques > Patch-Clamp Techniques

Preferred term

Patch-Clamp Techniques  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Clamp Technique, Patch
  • Clamp Techniques, Patch
  • Patch Clamp Technic
  • Patch-Clamp Technic
  • Patch Clamp Technics
  • Patch-Clamp Technics
  • Patch Clamp Technique
  • Patch-Clamp Technique
  • Patch Clamp Techniques
  • Technic, Patch-Clamp
  • Technics, Patch-Clamp
  • Technique, Patch Clamp
  • Technique, Patch-Clamp
  • Techniques, Patch Clamp
  • Techniques, Patch-Clamp

Note

  • a cytol technique for removing a tiny patch of plasma membrane; NIM

Scope note

  • An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.

History note

  • 95

In other languages

URI

http://www.yso.fi/onto/mesh/D018408

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