Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Hemic and Lymphatic Diseases > Hematologic Diseases > Blood Coagulation Disorders > Protein S Deficiency
Hemic and Lymphatic Diseases > Hematologic Diseases > Blood Protein Disorders > Protein S Deficiency
Hemic and Lymphatic Diseases > Hematologic Diseases > Thrombophilia > Protein S Deficiency

Preferred term

Protein S Deficiency  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Deficiencies, Protein S
  • Deficiency, Protein S
  • Hereditary Thrombophilia Due To Protein S Deficiency
  • Protein S Deficiencies

Scope note

  • An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embolism. PROTEIN S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated PROTEIN C (also a vitamin K-dependent protein), and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine, 12th ed, p1511; Wintrobe's Clinical Hematology, 9th ed, p1523)

History note

  • 95

In other languages

URI

http://www.yso.fi/onto/mesh/D018455

Download this concept:

RDF/XML TURTLE JSON-LD Created 4/16/94, last modified 7/8/13