Concept information
Preferred term
PrPC Proteins
Type
-
Topical Descriptor
Broader concept
Entry terms
- Cp 33-35
- Cp33-35, Scrapie
- PrP sen
- PrP-sen
- Scrapie Amyloid Precursor Protein
Note
- PrPC stands for PRion Protein Cellular; do not confuse with PRPSC PROTEINS which are scrapie prion proteins
Scope note
- Normal cellular isoform of PRION PROTEINS encoded by a chromosomal gene and found in normal and scrapie-infected brain tissue, and other normal tissue. PrPC are protease-sensitive proteins whose function is unknown. Posttranslational modification of PrPC into PrPSC leads to infectivity.
History note
- 95; SCRAPIE AMYLOID PRECURSOR PROTEIN was NM 1989-94
In other languages
-
Finnish
-
PrPC-proteiini
-
Swedish
URI
http://www.yso.fi/onto/mesh/D018621
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