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Concept information

Preferred term

PrPC Proteins  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Cp 33-35
  • Cp33-35, Scrapie
  • PrP sen
  • PrP-sen
  • Scrapie Amyloid Precursor Protein

Note

  • PrPC stands for PRion Protein Cellular; do not confuse with PRPSC PROTEINS which are scrapie prion proteins

Scope note

  • Normal cellular isoform of PRION PROTEINS encoded by a chromosomal gene and found in normal and scrapie-infected brain tissue, and other normal tissue. PrPC are protease-sensitive proteins whose function is unknown. Posttranslational modification of PrPC into PrPSC leads to infectivity.

History note

  • 95; SCRAPIE AMYLOID PRECURSOR PROTEIN was NM 1989-94

In other languages

URI

http://www.yso.fi/onto/mesh/D018621

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RDF/XML TURTLE JSON-LD Created 4/16/94, last modified 6/13/16