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Biological Factors > Intercellular Signaling Peptides and Proteins > Cytokines > Interleukins > Interleukin-12
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Cytokines > Interleukins > Interleukin-12
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Cytokines > Interleukins > Interleukin-12

Preferred term

Interleukin-12  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • Cytotoxic Lymphocyte Maturation Factor
  • IL 12
  • IL-12
  • IL12
  • IL-12 p70
  • Interleukin 12
  • Interleukin 12 p70
  • Interleukin-12 p70
  • Natural Killer Cell Stimulatory Factor

Scope note

  • A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS.

History note

  • 1995 (1991)

In other languages

URI

http://www.yso.fi/onto/mesh/D018664

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