Concept information
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Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
ErbB Receptors
Preferred term
Receptor, ErbB-2
Type
-
Topical Descriptor
Broader concept
Entry terms
- Antigens, CD340
- CD340 Antigen
- CD340 Antigens
- c erbB 2 Protein
- c-erbB-2 Protein
- erbB 2 Proto Oncogene Protein
- erbB-2 Proto-Oncogene Protein
- erbB 2 Receptor Protein Tyrosine Kinase
- erbB-2 Receptor Protein-Tyrosine Kinase
- erbB-2 Receptors
- Erb b2 Receptor Tyrosine Kinases
- Erb-b2 Receptor Tyrosine Kinases
- HER 2 Proto Oncogene Protein
- HER-2 Proto-Oncogene Protein
- Metastatic Lymph Node Gene 19 Protein
- neu Proto Oncogene Protein
- neu Proto-Oncogene Protein
- Neu Receptor
- Oncogene Protein HER 2
- Oncogene Protein HER-2
- p185(c-neu)
- p185erbB2 Protein
- Proto-Oncogene Protein, erbB-2
- Proto Oncogene Protein HER 2
- Proto-Oncogene Protein HER-2
- Proto-Oncogene Protein, HER-2
- Proto-oncogene Protein Neu
- Proto-Oncogene Protein, neu
- Proto-Oncogene Protein p185(neu)
- Proto Oncogene Proteins c erbB 2
- Proto-Oncogene Proteins c-erbB-2
- Receptor, Neu
- Receptors, erbB-2
- Tyrosine Kinase type Cell Surface Receptor HER2
- Tyrosine Kinase-type Cell Surface Receptor HER2
Scope note
- A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member.
History note
- 2019 (1995)
In other languages
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Finnish
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Swedish
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Receptor, erbB-2
URI
http://www.yso.fi/onto/mesh/D018719
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