Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Genetic Phenomena > Genetic Variation > Genetic Heterogeneity

Preferred term

Genetic Heterogeneity  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Genetic Heterogeneities
  • Heterogeneities, Genetic
  • Heterogeneity, Genetic

Scope note

  • The presence of apparently similar characters for which the genetic evidence indicates that different genes or different genetic mechanisms are involved in different pedigrees. In clinical settings genetic heterogeneity refers to the presence of a variety of genetic defects which cause the same disease, often due to mutations at different loci on the same gene, a finding common to many human diseases including ALZHEIMER DISEASE; CYSTIC FIBROSIS; LIPOPROTEIN LIPASE DEFICIENCY, FAMILIAL; and POLYCYSTIC KIDNEY DISEASES. (Rieger, et al., Glossary of Genetics: Classical and Molecular, 5th ed; Segen, Dictionary of Modern Medicine, 1992)

History note

  • 95

In other languages

URI

http://www.yso.fi/onto/mesh/D018740

Download this concept:

RDF/XML TURTLE JSON-LD Created 4/19/94, last modified 7/8/08