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... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Neurotransmitter Agents > GABA Agents > GABA Modulators
... > Chemical Actions and Uses > Pharmacologic Actions > Molecular Mechanisms of Pharmacological Action > Neurotransmitter Agents > GABA Agents > GABA Modulators

Preferred term

GABA Modulators  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Acid Modulators, gamma-Aminobutyric
  • GABAergic Modulators
  • gamma Aminobutyric Acid Modulators
  • gamma-Aminobutyric Acid Modulators
  • Modulators, GABAergic
  • Modulators, gamma-Aminobutyric Acid

Note

  • general or unspecified; prefer specifics

Scope note

  • Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here.

History note

  • 95

In other languages

  • GABA-muuntajat

    Finnish

  • GABA-modulaattori
  • GABA-modulaattorit
  • GABA-muuntaja
  • gamma-aminovoihappomodulaattori
  • gamma-aminovoihappomodulaattorit
  • gamma-aminovoihappomuuntaja
  • gamma-aminovoihappomuuntajat
  • GABA-modulatorer

    Swedish

URI

http://www.yso.fi/onto/mesh/D018757

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