Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Endocrine System Diseases > Endocrine Gland Neoplasms > Multiple Endocrine Neoplasia > Multiple Endocrine Neoplasia Type 1
Neoplasms > Neoplasms by Site > Endocrine Gland Neoplasms > Multiple Endocrine Neoplasia > Multiple Endocrine Neoplasia Type 1
Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Genetic Diseases, Inborn > Neoplastic Syndromes, Hereditary > Multiple Endocrine Neoplasia > Multiple Endocrine Neoplasia Type 1
Neoplasms > Neoplastic Syndromes, Hereditary > Multiple Endocrine Neoplasia > Multiple Endocrine Neoplasia Type 1
Neoplasms > Neoplasms, Multiple Primary > Multiple Endocrine Neoplasia > Multiple Endocrine Neoplasia Type 1

Preferred term

Multiple Endocrine Neoplasia Type 1  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Multiple Endocrine Neoplasia Type I
  • Multiple Endocrine Neoplasms Type 1
  • Neoplasia, Multiple Endocrine Type 1
  • Neoplasms, Multiple Endocrine Type 1
  • Neoplasms, Multiple Endocrine Type I
  • Wermer Syndrome

Note

  • coordinate IM with specific endocrine/neoplasm pre-coordinates (IM) + specific histological type (IM) if pertinent

Scope note

  • A form of multiple endocrine neoplasia that is characterized by the combined occurrence of tumors in the PARATHYROID GLANDS, the PITUITARY GLAND, and the PANCREATIC ISLETS. The resulting clinical signs include HYPERPARATHYROIDISM; HYPERCALCEMIA; HYPERPROLACTINEMIA; CUSHING DISEASE; GASTRINOMA; and ZOLLINGER-ELLISON SYNDROME. This disease is due to loss-of-function of the MEN1 gene, a tumor suppressor gene (GENES, TUMOR SUPPRESSOR) on CHROMOSOME 11 (Locus: 11q13).

History note

  • 95; MEA I, MEN I, & WERMER SYNDROME were see NEOPLASMS, MULTIPLE ENDOCRINE 1983-94

In other languages

URI

http://www.yso.fi/onto/mesh/D018761

Download this concept:

RDF/XML TURTLE JSON-LD Created 5/23/94, last modified 2/24/17