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Concept information

Preferred term

Genes, erbA  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • erbA Genes

Note

  • erbA stands for "ERythroBlastosis virus, Avian"; GENES, ERBB & its specifics are also available; in titles & translations spell as erbA

Scope note

  • Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS, AVIAN), v-erbA. In cells, erbA genes encode thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsiveness but not DNA binding capacity.

History note

  • 95

In other languages

  • Finnish

  • erbA-geeni
  • Swedish

  • c-erbA gener
  • c-erbA proto-onkogener
  • erbA-alfa gener
  • erbA-beta gener
  • THRA gener
  • THRB gener
  • TR-alfa gener
  • TR-beta gener
  • v-erbA gener
  • v-erbA onkogener
  • webA-beta gener

URI

http://www.yso.fi/onto/mesh/D018776

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RDF/XML TURTLE JSON-LD Created 5/23/94, last modified 7/8/08