Concept information
Preferred term
Polymorphism, Single-Stranded Conformational
Type
-
Topical Descriptor
Broader concept
Entry terms
- Conformational Polymorphism, Single-Stranded
- Conformational Polymorphisms, Single-Stranded
- Polymorphisms, Single-Stranded Conformational
- Single Stranded Conformational Polymorphism
- Single-Stranded Conformational Polymorphism
- Single-Stranded Conformational Polymorphisms
- SSCP
Note
- POLYMORPHISM, SINGLE NUCLEOTIDE is also available
Scope note
- Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.
History note
- 1995
In other languages
-
Finnish
-
yksijuoste-konformaatiopolymorfismi
-
yksijuosteisen DNA:n rakenteellinen monimuotoisuus
-
yksisäie-konformaatiopolymorfismi
-
yksisäikeisen DNA:n rakennepolymorfismi
-
yksisäikeisen DNA:n rakenteellinen monimuotoisuus
-
Swedish
-
SSCP
URI
http://www.yso.fi/onto/mesh/D018807
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