Concept information
Preferred term
Transcription Factor AP-1
Type
-
Topical Descriptor
Broader concept
Entry terms
- Activator Protein 1
- Activator Protein-1
- AP-1
- AP 1 Enhancer Binding Protein
- AP-1 Enhancer Binding Protein
- AP-1 Enhancer-Binding Protein
- Enhancer-Binding Protein, AP-1
Scope note
- A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins must dimerize in order to bind to the AP-1 recognition site, also known as the TPA-responsive element (TRE). AP-1 controls both basal and inducible transcription of several genes.
History note
- 95; was TRANSCRIPTION FACTOR, AP-1 see PROTO-ONCOGENE PROTEINS C-JUN 1992-94; AP-1 ENHANCER-BINDING PROTEIN was see PROTO-ONCOGENE PROTEINS C-JUN 1992-94
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D018808
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