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Biological Factors > Biomarkers > Biomarkers, Tumor > Proliferating Cell Nuclear Antigen
Biological Factors > Antigens > Antigens, Nuclear > Proliferating Cell Nuclear Antigen
Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Antigens, Nuclear > Proliferating Cell Nuclear Antigen

Preferred term

Proliferating Cell Nuclear Antigen  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Antigen, Proliferating Cell Nuclear
  • PCNA

Scope note

  • Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types.

History note

  • 95; was PROLIFERATING CELL NUCLEAR ANTIGEN (NM) 1983-94

In other languages

URI

http://www.yso.fi/onto/mesh/D018809

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RDF/XML TURTLE JSON-LD Created 5/31/94, last modified 6/19/15