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Endocrine System Diseases > Endocrine Gland Neoplasms > Multiple Endocrine Neoplasia > Multiple Endocrine Neoplasia Type 2b
Neoplasms > Neoplasms by Site > Endocrine Gland Neoplasms > Multiple Endocrine Neoplasia > Multiple Endocrine Neoplasia Type 2b
Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Genetic Diseases, Inborn > Neoplastic Syndromes, Hereditary > Multiple Endocrine Neoplasia > Multiple Endocrine Neoplasia Type 2b
Neoplasms > Neoplastic Syndromes, Hereditary > Multiple Endocrine Neoplasia > Multiple Endocrine Neoplasia Type 2b
Neoplasms > Neoplasms, Multiple Primary > Multiple Endocrine Neoplasia > Multiple Endocrine Neoplasia Type 2b

Preferred term

Multiple Endocrine Neoplasia Type 2b  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • MEA 2b
  • MEA IIb
  • MEN 2b
  • MEN2b
  • MEN 3
  • MEN IIb
  • MEN III
  • Mucosal Neuroma Syndrome
  • Mucosal Neuroma Syndromes
  • Multiple Endocrine Neoplasia, Type 2b
  • Multiple Endocrine Neoplasia, Type IIb
  • Multiple Endocrine Neoplasms Type 2b
  • Neoplasia, Multiple Endocrine Type 2b
  • Neoplasms, Multiple Endocrine Type 2b
  • Neuroma Syndrome, Mucosal
  • Neuromata, Mucosal, With Endocrine Tumors
  • Syndrome, Wagenmann-Froboese
  • Wagenmann Froboese Syndrome
  • Wagenmann-Froboese Syndrome

Note

  • coordinate IM with specific endocrine/neoplasm pre-coordinates (IM) + specific histological type (IM) if pertinent

Scope note

  • Similar to MEN2A, it is also caused by mutations of the MEN2 gene, also known as the RET proto-oncogene. Its clinical symptoms include medullary carcinoma (CARCINOMA, MEDULLARY) of THYROID GLAND and PHEOCHROMOCYTOMA of ADRENAL MEDULLA (50%). Unlike MEN2a, MEN2b does not involve PARATHYROID NEOPLASMS. It can be distinguished from MEN2A by its neural abnormalities such as mucosal NEUROMAS on EYELIDS; LIP; and TONGUE, and ganglioneuromatosis of GASTROINTESTINAL TRACT leading to MEGACOLON. It is an autosomal dominant inherited disease.

History note

  • 1995; MEA III & MEN III see NEOPLASMS, MULTIPLE ENDOCRINE 1983-1994

In other languages

  • MEN 2B -oireyhtymä

    Finnish

  • MEN 2b
  • MEN 2B
  • MEN 2b -oireyhtymä
  • MEN 2b -syndrooma
  • MEN 2B -syndrooma
  • MEN-2b
  • MEN-2B
  • MEN2b
  • monikasvainoireyhtymä 2b
  • monikasvainoireyhtymä 2B
  • multippeli endokriininen neoplasia tyyppi 2b
  • multippeli endokriininen neoplasia tyyppi 2B
  • Multipla hormonella tumörer typ 2b

    Swedish

  • Multipel endokrin neoplasi typ 2b

URI

http://www.yso.fi/onto/mesh/D018814

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