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Concept information

Cells > Cells, Cultured > Spheroids, Cellular

Preferred term

Spheroids, Cellular  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Multicellular Spheroid
  • Multicellular Spheroids
  • Spheroid, Multicellular
  • Spheroids, Multicellular

Note

  • do not confuse with "spheroid bodies" referring to axons in neuropathol; if tumor spheroids coordinate with TUMOR CELLS, CULTURED

Scope note

  • Spherical, heterogeneous aggregates of proliferating, quiescent, and necrotic cells in culture that retain three-dimensional architecture and tissue-specific functions. The ability to form spheroids is a characteristic trait of CULTURED TUMOR CELLS derived from solid TUMORS. Cells from normal tissues can also form spheroids. They represent an in-vitro model for studies of the biology of both normal and malignant cells. (From Bjerkvig, Spheroid Culture in Cancer Research, 1992, p4)

History note

  • 2004(1996)

In other languages

URI

http://www.yso.fi/onto/mesh/D018874

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