Concept information
Preferred term
CD59 Antigens
Type
-
Topical Descriptor
Broader concept
Entry terms
- Antigens, CD59
- CD59 Antigen
- Homologous Restriction Factor 20
- HRF20
- MACIF
- Membrane Attack Complex Inhibition Factor
- Membrane Inhibitor of Reactive Lysis
- Protectin
Scope note
- Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234)
History note
- 2018 (1990); for PROTECTIN use CATIONIC PROTEIN, URATE-CALCIUM OXALATE STONE 1996-1999
In other languages
-
Finnish
-
CD59
-
CD59-antigeeni
-
Swedish
-
Antigener, CD59
URI
http://www.yso.fi/onto/mesh/D018957
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