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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptor Protein-Tyrosine Kinases > Proto-Oncogene Proteins c-kit
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Proto-Oncogene Proteins c-kit
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Proto-Oncogene Proteins c-kit
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Proto-Oncogene Proteins c-kit
... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Oncogene Proteins > Proto-Oncogene Proteins > Proto-Oncogene Proteins c-kit
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Peptide > Receptors, Growth Factor > Receptors, Colony-Stimulating Factor > Proto-Oncogene Proteins c-kit
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Cytokine > Receptors, Colony-Stimulating Factor > Proto-Oncogene Proteins c-kit

Preferred term

Proto-Oncogene Proteins c-kit  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Antigens, CD117
  • CD117 Antigen
  • CD117 Antigens
  • c-kit, p145
  • c kit Protein
  • c-kit Protein
  • c-kit, Proto-Oncogene Protein
  • c kit Receptor
  • c-kit Receptor
  • kit Proto Oncogene Protein
  • kit Proto-Oncogene Protein
  • p145 c kit
  • p145 c-kit
  • p145(c-kit)
  • p145c kit
  • p145c-kit
  • Proto Oncogene Protein c kit
  • Proto-Oncogene Protein c-kit
  • Proto Oncogene Protein kit
  • Proto-Oncogene Protein kit
  • Proto-Oncogene Protein, kit
  • Receptor, Stem Cell Factor
  • SCF Receptor
  • Stem Cell Factor Receptor

Scope note

  • A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEINS C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.

History note

  • 2000(1996); use PROTO-ONCOGENE PROTEIN c-KIT (NM) 1989-1995

In other languages

URI

http://www.yso.fi/onto/mesh/D019009

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