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Biological Factors > Immune Checkpoint Proteins > CD40 Antigens
Amino Acids, Peptides, and Proteins > Proteins > Immune Checkpoint Proteins > CD40 Antigens
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Cytokine > Receptors, Tumor Necrosis Factor > CD40 Antigens
... > Biological Factors > Antigens > Antigens, Surface > Antigens, Differentiation > Antigens, Differentiation, B-Lymphocyte > CD40 Antigens
Biological Factors > Biomarkers > Antigens, Differentiation > Antigens, Differentiation, B-Lymphocyte > CD40 Antigens

Preferred term

CD40 Antigens  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Antigen, CD40
  • Antigen, CDw40
  • Antigens, CD40
  • CD40 Antigen
  • CDw40 Antigen
  • Receptor, TNFRSF5
  • TNFRSF5 Receptor
  • Tumor Necrosis Factor Receptor Superfamily, Member 5

Scope note

  • Members of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. They are found on mature B-LYMPHOCYTES, some EPITHELIAL CELLS; and lymphoid DENDRITIC CELLS. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centers. Mutations in the CD40 antigen gene result in HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 3. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.

History note

  • 2018 (1988)

In other languages

URI

http://www.yso.fi/onto/mesh/D019013

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