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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Death Domain > fas Receptor
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Cytokine > Receptors, Tumor Necrosis Factor > fas Receptor

Preferred term

fas Receptor  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Antigens, CD95
  • APO 1 Antigen
  • APO-1 Antigen
  • CD95 Antigen
  • CD95 Antigens
  • fas Antigen
  • fas Antigens
  • Fas Cell Surface Death Receptor
  • fas Receptors
  • Receptors, fas
  • Receptor, TNFRSF6
  • TNFRSF6 Receptor
  • Tumor Necrosis Factor Receptor Superfamily, Member 6

Scope note

  • A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome.

History note

  • 2018 (1989)

In other languages

URI

http://www.yso.fi/onto/mesh/D019014

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