Skip to main content

Search from vocabulary

Content language

Concept information

Preferred term

Platelet Glycoprotein GPIb-IX Complex  

Type

  • Topical Descriptor

Entry terms

  • Glycoprotein Ib IX Complex
  • Glycoprotein Ib-IX Complex

Scope note

  • Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides, GPIb alpha, GPIb beta, and GPIX. Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin. Congenital deficiency of the GPIb-IX complex results in Bernard-Soulier syndrome. The platelet glycoprotein GPV associates with GPIb-IX and is also absent in Bernard-Soulier syndrome.

History note

  • 96; PLATELET MEMBRANE GLYCOPROTEIN IB was see PLATELET MEMBRANE GLYCOPROTEINS 1987-95

In other languages

URI

http://www.yso.fi/onto/mesh/D019038

Download this concept:

RDF/XML TURTLE JSON-LD Created 5/26/95, last modified 3/16/23