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... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structural Elements > Amino Acid Motifs > Helix-Loop-Helix Motifs > Helix-Turn-Helix Motifs
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structure, Secondary > Amino Acid Motifs > Helix-Loop-Helix Motifs > Helix-Turn-Helix Motifs

Preferred term

Helix-Turn-Helix Motifs  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • HTH Motif
  • HTH Motifs
  • Motif, HTH
  • Motifs, Helix Turn Helix
  • Motifs, Helix-Turn-Helix
  • Motifs, HTH

Note

  • do not confuse with HELIX-LOOP-HELIX MOTIFS

Scope note

  • The first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9)

History note

  • 96; was see HELIX-LOOP-HELIX MOTIFS 1994-95

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URI

http://www.yso.fi/onto/mesh/D019077

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RDF/XML TURTLE JSON-LD Created 5/26/95, last modified 5/31/16