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Concept information

Preferred term

Antibodies, Blocking  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Blocking Antibodies

Note

  • antibodies inhibiting reaction between antigen and other antibodies or sensitized T-lymphocytes: not for any antibody reaction to an antigen ( = ANTIBODIES or specific antibody); do not coordinate with ANTIBODY FORMATION for /biosyn

Scope note

  • Antibodies that inhibit the reaction between ANTIGEN and other antibodies or sensitized T-LYMPHOCYTES (e.g., antibodies of the IMMUNOGLOBULIN G class that compete with IGE antibodies for antigen, thereby blocking an allergic response). Blocking antibodies that bind tumors and prevent destruction of tumor cells by CYTOTOXIC T-LYMPHOCYTES have also been called enhancing antibodies. (Rosen et al., Dictionary of Immunology, 1989)

History note

  • 96

In other languages

URI

http://www.yso.fi/onto/mesh/D019138

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