Concept information
Preferred term
Troponin C
Type
-
Topical Descriptor
Broader concept
Entry terms
- Troponin-C
Note
- TROPONIN I & TROPONIN T are also available
Scope note
- A TROPONIN complex subunit that binds calcium and help regulate calcium-dependent muscle contraction. There are two troponin C subtypes: troponin C1 and C2. Troponin C1 is skeletal and cardiac type whereas troponin C2 is skeletal type. Troponin C1 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin C1 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
History note
- 97; was TROPONIN C (NM) 1975-96
In other languages
-
Finnish
-
TnC
-
Swedish
URI
http://www.yso.fi/onto/mesh/D019209
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