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Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Proto-Oncogene Proteins c-bcl-2
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Proto-Oncogene Proteins c-bcl-2
... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Oncogene Proteins > Proto-Oncogene Proteins > Proto-Oncogene Proteins c-bcl-2

Preferred term

Proto-Oncogene Proteins c-bcl-2  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • bcl 2 Proto Oncogene Proteins
  • bcl-2 Proto-Oncogene Proteins
  • c bcl 2 Proteins
  • c-bcl-2 Proteins
  • Proto-Oncogene Proteins, bcl-2

Scope note

  • Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPTOSIS. The proteins are found on mitochondrial, microsomal, and NUCLEAR MEMBRANE sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma.

History note

  • 97; was PROTO-ONCOGENE PROTEIN BCL-2 (NM) 1989-96

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URI

http://www.yso.fi/onto/mesh/D019253

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RDF/XML TURTLE JSON-LD Created 6/10/96, last modified 11/24/15