Concept information
Preferred term
Genes, bcl-2
Type
-
Topical Descriptor
Broader concept
Entry terms
- bcl-2 Gene
- bcl 2 Genes
- bcl-2 Genes
- Gene, bcl-2
Note
- bcl stands for "B-Cell Leukemia"
Scope note
- The B-cell leukemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18.
History note
- 97
In other languages
-
Finnish
-
bcl-2-geeni
-
Swedish
-
c-bcl-2 gener
-
c-bcl-2 proto-onkogener
URI
http://www.yso.fi/onto/mesh/D019254
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